Isaac (Zak) Kohane, MD, PhD

Professor and Chair, Department of Biomedical Informatics

Isaac “Zak” Kohane, MD, PhD, is the inaugural chair of Harvard Medical School’s Department of Biomedical Informatics, whose mission is to develop the methods, tools, and infrastructure required for a new generation of scientists and care providers to move biomedicine rapidly forward by taking advantage of the insight and precision offered by big data. Kohane develops and applies computational techniques to address disease at multiple scales, from whole health care systems to the functional genomics of neurodevelopment. He also has worked on AI applications in medicine since the 1990’s, including automated ventilator control, pediatric growth monitoring, detection of domestic abuse, diagnosing autism from multimodal data and most recently assisting clinicians using whole genome sequence and clinical histories to diagnose rare or unknown disease patients. He is the inaugural Editor-in-Chief of the New England Journal of Medicine AI and co-author of a recent book “The AI Revolution in Medicine. ” He is a member of the National Academy of Medicine, the American Society for Clinical Investigation and the American College of Medical Informatics.